Process for the preparation of 4-androstene-3,17-dione and 1,4-a

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing a...

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4352531, C12N 120, C12P 3316

Patent

active

054181453

ABSTRACT:
A process is claimed for the preparation of 4-androstene-3,17-dione and 1,4-androstadiene-3,17-dione of the general formula ##STR1## wherein symbolizes a single bond or a double bond, characterized by fermenting .alpha.-sitosterol with a culture of a strain of microorganisms capable of side chain degradation of sterols.

REFERENCES:
patent: 3684657 (1972-08-01), Kraychy
patent: 3759791 (1973-09-01), Marsheck
patent: 4345029 (1982-08-01), Woucha et al.
Goodfellow et al., The Biology of Actinomycetes Academic Press, 1984.

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