Process for the preparation of 4.5-diphenyloxazole-2-propanoic a

Details Process for the preparation of 4.5-diphenyloxazole-2-propanoic a Process for the preparation of 4.5-diphenyloxazole-2-propanoic a

1998-10-15

2000-08-01

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D26330

Patent

active

060968966

ABSTRACT:
In a process for the preparation of 4,5-diphenyloxazole-2-propanoic acid, the improvement consisting in using toluene in the esterification reaction of benzoin, and acetic acid/formic acid in the subsequent cyclization, thereby obtaining higher yields and avoiding the use and the disposal of high amounts of pyridine.

REFERENCES:
patent: 3578671 (1971-05-01), Brown
patent: 4190584 (1980-02-01), Weston

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