Process for the preparation of 3-(lpyroglutamyl)-L-thiazolidine-

Details Process for the preparation of 3-(lpyroglutamyl)-L-thiazolidine- Process for the preparation of 3-(lpyroglutamyl)-L-thiazolidine-

1990-10-09

1992-05-05

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548201, 548537, C07D27704, C07D27718, C07D20700

Patent

active

051109360

ABSTRACT:
3-(L-pyroglutamyl)-L-thiazolidine-4-carboxylic acid and derivatives thereof are prepared by condensing L-pyroglutamic acid or its substitution products, either in the presence of dicyclohexylcarbodiimmide or the like, or by condensation of active derivatives of L-pyroglutamic acid with 4-thiazolidine-carboxylic acid derivatives.

REFERENCES:
Chemical Abstracts, vol. 107: 198361n Pyroglutamide derivatives, procedure for their preparation, and their use as nootropics, Kimura et al. 1987.
Organic Chem. 2nd Ed., McMurry, p. 754, 1988.
CA vol. 113: 55406u Chromatographic . . . molecules, Schneider, 1989.
CA vol. 112: 34440g Electrically . . . culture, Schneider, 1989.

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