Process for the preparation of 3-cyano-4-aryl-pyrroles

Details Process for the preparation of 3-cyano-4-aryl-pyrroles Process for the preparation of 3-cyano-4-aryl-pyrroles

1989-01-05

1990-10-23

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546281, 548517, 548526, 548527, C07D20734, C07D40104, C07D40904, C07D40504

Patent

active

049653636

ABSTRACT:
A process for the preparation of a 3-cyano-4-arylpyrrole of the formula ##STR1## in which Ar is optionally substituted heteroaryl or aryl, comprising reacting an .alpha.-cyanocinnamamide of the formula ##STR2## with a sulphonylmethylisocyanide of the formula

REFERENCES:
patent: 4680413 (1987-07-01), Genda et al.
Zabicky, J. Chem Soc. 1961, 683.
Greenlee, J. Org. Chem. 46, 5351-5353 (1981).
Derwent for JP-61-030571.

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