Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1979-10-17
1981-08-11
Daus, Donald G.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
26032614T, 26032613B, C07D20918, C07D20920
Patent
active
042833361
ABSTRACT:
The compounds having Formula I, ##STR1## wherein X is a fluorine or methoxy group, and R is a hydrogen or methyl group, such that R is hydrogen only when X is fluorine are novel. The compounds having Formula I and their acid addition salts are useful for the treatment of hypertension. Processes for the preparation of the compounds having Formula I and useful intermediates are described.
REFERENCES:
Roshkov et al, J. of Org. Chem. of USSR, 12, 1976, pp. 1076-1079, (Translation pp. 1087-1089).
Hong Enrique
Safdy Max E.
Schut Robert N.
Daus Donald G.
Jeffers Jerome L.
Miles Laboratories Inc.
Springer D. B.
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