Process for the preparation of 3-acetoxy-2-methylbenzoyl chlorid

Details Process for the preparation of 3-acetoxy-2-methylbenzoyl chlorid Process for the preparation of 3-acetoxy-2-methylbenzoyl chlorid

1998-07-13

2000-04-18

Keys, Rosalynd

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C07C 69017

Patent

active

060517328

ABSTRACT:
The present invention relates to a process for the preparation of 3-acetoxy-2-methylbenzoyl chloride by reacting an alkali metal salt of 3-aminonaph-thalene-1,5-disulfonic acid with alkali metal hydroxide and water in the weight ratio 1:(1 to 1.6):(1 to 1.6) at 220 to 320.degree. C. to give the dialkali metal salt of the 3-hydroxy-2-methylbenzoic acid, separating off insoluble constituents from the reaction mixture, then adjusting the reaction mixture to a pH of 11.5 to 13.5 by addition of acid and reacting with acetic anhydride at -5 to +25.degree. C., precipitating the 3-acetoxy-2-methylbenzoic acid by addition of acid, separating off the 3-acetoxy-2-methylbenzoic acid and reacting it with an inorganic acid chloride to give 3-acetoxy-2-methylbenzoyl chloride.

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