Process for the preparation of 3,4-dihydroxybutanoic acid and sa

Details Process for the preparation of 3,4-dihydroxybutanoic acid and sa Process for the preparation of 3,4-dihydroxybutanoic acid and sa

1992-10-26

1994-06-07

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549326, C07D30512

Patent

active

053191102

ABSTRACT:
A process for the preparation of 3,4-dihydroxybutanoic acid (1) and salts thereof from a glucose source containing 1,4-linked glucose as a substituent is described. The process uses an alkali metal hdyroxide and hydrogen peroxide to convert the glucose source to (1). The compound (1) is useful as a chemical intermediate to naturally occurring fatty acids and is used to prepare 3,4-dihydroxybutanoic acid-gamma-lactone (2) and furanone (3), particularly stereoisomers of these compounds.

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