Process for the preparation of 3,4-dihydro-2-substituted-2H-1,2-

Details Process for the preparation of 3,4-dihydro-2-substituted-2H-1,2- Process for the preparation of 3,4-dihydro-2-substituted-2H-1,2-

1984-07-13

1987-07-28

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544 48, 544 49, C07D27902, C07D51304

Patent

active

046833064

ABSTRACT:
Process for the preparation of 3,4-dihydro-2-substituted-4(or 3)-oxo-2H-1,2-thiazine-3(or 4)-carboxylic acid 1,1,-dioxide magnesium chelate derivatives and its acids by reacting appropriately 3,4-dihydro-2-substituted-4(or 3)-oxo-2H-1,2-thiazine 1,1-dixoides with alkylmagnesiumcarbonate and then hydrolyzing and its use as intermediates for the preparation of N-substituted-2-substituted-2H-1,2-thiazine-3(or 4)-carboxamide-1,1-dioxide derivatives, effective antiinflammatory agents.

REFERENCES:
patent: 3501466 (1970-03-01), Rasmussen
patent: 3892740 (1975-07-01), Lombardino
patent: 3898218 (1975-08-01), Kaminsky
patent: 3900470 (1975-08-01), Rasmussen
patent: 3992535 (1976-11-01), Trummlitz et al.
patent: 4137313 (1979-01-01), Trummlitz et al.
patent: 4259336 (1981-03-01), Engel et al.
patent: 4309427 (1982-01-01), Lombardino
patent: 4478996 (1984-10-01), Almenara

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