Process for the preparation of 2-oxytetrahydrofurans

Details Process for the preparation of 2-oxytetrahydrofurans Process for the preparation of 2-oxytetrahydrofurans

1992-04-13

1993-10-19

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549507, C07D30720, C07D30728

Patent

active

052547027

ABSTRACT:
A two-phase process for preparing 2-oxytetrahydrofurans is disclosed. Aqueous 4-hydroxybutanal, which is readily available from a commercial hydroformylation process, is combined with an organic solution of a hydroxy compound in the presence of an acid catalyst to produce a 2-oxytetrahydrofuran. 2-Oxytetrahydrofurans are useful intermediates for pharmaceuticals or for the synthesis of 2,3-dihydrofuran.

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