Process for the preparation of 2-hydroxypyridine or quinoline co

Details Process for the preparation of 2-hydroxypyridine or quinoline co Process for the preparation of 2-hydroxypyridine or quinoline co

1989-04-10

1990-11-06

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546170, 546298, 546299, C07D213803

Patent

active

049688030

ABSTRACT:
The present invention relates to a process for the preparation of hydroxypyridine based compounds. The process comprises the step of: in water, reacting a pyridine based compound with the proviso that the second position on the nitrogen ring is unsubstituted and the fourth position in the nitrogen ring is not substituted with halogen, with elemental fluorine at a temperature of about -25.degree. to about +30.degree. C. for a time sufficient to form a 2-hydroxypyridine based compound.
The resulting 2-hydroxypyridine or quinoline carboxylic acids and esters are useful as herbicide and pharmaceutical intermediates.

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