Process for the preparation of 2-halogenated ergoline derivative

Details Process for the preparation of 2-halogenated ergoline derivative Process for the preparation of 2-halogenated ergoline derivative

1987-06-05

1989-03-28

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

546 67, 546 68, 546 69, 260694, C07D45702, C07D45704

Patent

active

048165875

ABSTRACT:
The invention relates to a novel process for the halogenation in 2-position of ergot alkaloids. The process is characterized by that as a halogenating agent a system consisting of dimethylsulfoxide, a trialkylhalosilane or triarylhalosilane and optionally a hydrogen halide is used.

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