Process for the preparation of 2-chloro-1,3-dimethoxybenzene

Details Process for the preparation of 2-chloro-1,3-dimethoxybenzene Process for the preparation of 2-chloro-1,3-dimethoxybenzene

1984-08-13

1986-04-01

Helfin, Bernard

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

C07C 4122

Patent

active

045799814

ABSTRACT:
An improved process for the preparation of 2-chloro-1,3-dimethoxybenzene involving the reaction of [2,6-dimethoxyphenyl]lithium with chlorinating agents is disclosed. 2-Chloro-1,3-dimethoxybenzene is useful as a starting material for the synthesis of pharmacologically valuable 1,2-benzisoxazoloxyacetic acids.

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Weygand/Hilgetag, Preparative Organic Chemistry, (1972), 758-759.

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