Process for the preparation of 2-aminomethylpiperidine

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D21102

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053747283

ABSTRACT:
A process for the preparation of 2-aminomethylpiperidine by catalytic hydrogenation of 2-cyanopyridine in the presence of a cobalt-containing catalyst at elevated temperature and under elevated pressure. The reaction can be carried out either in two steps or in a single stage.

REFERENCES:
patent: 2507631 (1950-05-01), Hartmann et al.
patent: 3246000 (1966-04-01), Baizer
patent: 3717593 (1973-02-01), Zondler et al.
patent: 3890329 (1975-06-01), Benezra
Chemical Abstracts, vol. 106, 1987, Abstract #176178K JPA-86-251,663 ; Nov. 8, 1986.

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