Process for the preparation of 2-amino-3-chlorobenzoic acid

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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C07C 6304

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active

052330834

ABSTRACT:
The present invention relates to a process for the preparation of 2-amino-3-chlorobenzoic acid by dissolving 1 mol of 2,3-dichlorobenzoic acid in about 400 to about 2000 parts of water with at least the equimolar amount of an alkali metal hydroxide or with an aqueous solution of the equimolar amount of an alkali metal hydroxide, and subsequently reacting it with about 500 to about 2500 mol % of ammonia at temperatures of about 150.degree. to about 220.degree. C. in the presence of copper bronze, copper(I) salts and/or copper(II) salts.

REFERENCES:
patent: 4990661 (1991-02-01), Petersen et al.
patent: 4990663 (1991-02-01), Chang et al.
patent: 5068392 (1991-11-01), McKendry et al.

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