Process for the preparation of 2-alkylthio-4-hydrazino-5-fluorop

Details Process for the preparation of 2-alkylthio-4-hydrazino-5-fluorop Process for the preparation of 2-alkylthio-4-hydrazino-5-fluorop

1992-03-06

1992-10-13

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C07D23947

Patent

active

051552213

ABSTRACT:
2-Alkylthio-4-hydrazino-5-fluoropyrimidines can be prepared from 2,4-dichloro-5-fluoropyrimidine in good yield with high selectivity by treatment with 2 equivalents of alkyl mercaptan in the presence of base followed by treatment with hydrazine.

REFERENCES:
patent: 3040026 (1962-06-01), Duschinsky
patent: 5010195 (1991-04-01), Van Heertum et al.

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