Process for the preparation of 2-alkoxybenzosulfonamides

Details Process for the preparation of 2-alkoxybenzosulfonamides Process for the preparation of 2-alkoxybenzosulfonamides

1986-03-05

1987-11-24

Sutto, Anton H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C07C14378

Patent

active

047090928

ABSTRACT:
In accordance with a novel process, 2-alkoxybenzosulfonamides of formula I ##STR1## wherein R is chloromethyl, methoxymethyl, C.sub.1 -C.sub.4 alkyl or trifluoromethyl, are prepared by reacting a 4-alkoxychlorobenzene of formula II ##STR2## with chlorosulfonic acid ClSO.sub.3 H, converting the resultant sulfonyl chloride of formula III ##STR3## by reaction with ammonia into the sulfonamide of formula IV ##STR4## and hydrogenating said sulfonamide with hydrogen, in the presence of a precious metal catalyst.

REFERENCES:
patent: 4476321 (1984-10-01), Meyer et al.
patent: 4510325 (1985-04-01), Meyer et al.
patent: 4556733 (1985-12-01), Sullivan et al.

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