Process for the preparation of 2,5-dideoxystreptamine and of a n

Details Process for the preparation of 2,5-dideoxystreptamine and of a n Process for the preparation of 2,5-dideoxystreptamine and of a n

1974-02-15

1978-05-30

Hines, Robert V.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26034854, 424180, 536 12, 548373, C07C 9114

Patent

active

040923592

ABSTRACT:
The aminocyclitol 2,5-dideoxystreptamine may be prepared by a novel two-step synthesis from cis-4,8-dioxatricyclo [5.1.0.0.sup.3,5 ]octane. The aminocyclitol and a novel intermediate in the synthesis thereof are utilized by a Micromonospora inyoensis (M. inoyensis strain 155OF-1G NRRL 5742) for the elaboration of a novel antibacterial agent designated Mutamicin 2.

REFERENCES:
hirashi Ogawa et al., "Chemical Abstracts," vol. 53, pp. 18877-18878 (1959).
Haskell et al., "Jour. Amer. Chemical Society," vol. 81, pp. 3481-3483 (1959).
Craig et al., "Journal Organic Chemistry," vol. 32, No. 12, pp. 3743-3749 (1967).

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