Process for the preparation of 2,3,5-trimethylhydroquinone diest

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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560231, C07C 6748

Patent

active

061039241

ABSTRACT:
Preparation of 2,3,5-trimethylhydroquinone diesters by rearrangement of 2,6,6-trimethylcyclohex-2-ene-1,4-dione (4-oxo-isophorone, ketoisophorone) in the presence of a solid, acid catalyst and an acylating agent, for example carboxylic acid anhydrides or carboxylic acid halides. The 2,3,5-trimethylhydroquinone diester may then optionally be saponified to the free 2,3,5-trimethylhydroquinone, which is a valuable building block in the synthesis of vitamin E.

REFERENCES:
patent: T900015 (1972-07-01), Thwcatt
patent: 4247720 (1981-01-01), Baudouin
patent: 5908956 (1999-06-01), Takahashi

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