Process for the preparation of 2-(1-phenylethyl)hydroquinone and

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

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568747, 568763, 568766, C07C 3914, C07C 3714

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active

052351165

ABSTRACT:
Provided is an improved process for preparing 2-(1-phenylethyl)hydroquinone and its diacetate salt. In this process, the differential solubility of product and starting materials hydroquinone and styrene in non-polar organic solvents is utilized to provide mono-alkylated materials which can be easily removed from the reaction mixture. A solid acid catalyst is also used which allows the isolation of product and recycle of unreacted starting materials to be accomplished on an industrial-scale continuous process.

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Hawthorne and Reintjes, Journal of the Am. Chem. Soc. 87(20), pp. 4585-4587 (1965), "The Preparation of Alkylhydroquinones by the Reductive Alkylation of Quinones with Trialkylboranes".

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