Process for the preparation of (1S, 4R)-4-hydroxy-2-cyclopenteny

Details Process for the preparation of (1S, 4R)-4-hydroxy-2-cyclopenteny Process for the preparation of (1S, 4R)-4-hydroxy-2-cyclopenteny

1985-05-15

1986-10-21

Shaver, Paul F.

Organic compounds -- part of the class 532-570 series

Organic compounds

Silicon containing

C07F 708, C07F 718, C07F 704

Patent

active

046186905

ABSTRACT:
Optically pure (1S, 4R)-4-hydroxy-2-cyclopentyl ester of the formula ##STR1## in which Ac is an aliphatic acyl radical having 1 to 18 carbon atoms,
is produced by contacting a meso such as porcine liver esterase. The products are useful in synthesizing cyclopentanoid products such as brefeldin A, sesquiterpenes and prostaglandins.

REFERENCES:
patent: 4197245 (1980-04-01), Wissner
patent: 4202988 (1980-05-01), Wissner et al.

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