Process for the preparation of 16.beta.-methylsteroids

Details Process for the preparation of 16.beta.-methylsteroids Process for the preparation of 16.beta.-methylsteroids

1995-05-18

1997-01-21

Prior, Kimberly J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Cyclopentanohydrophenanthrene ring system containing

C07J 7500

Patent

active

055961088

ABSTRACT:
A new process for the preparation of 16.beta.-methyl-steroids of the formula ##STR1## and novel intermediates therefor which compounds are intermediates for betamethasone.

REFERENCES:
Swaminathan, et al, Tetrahedron, vol. 43 (16), pp. 3827-3838 (1987).
Lokos, et al, Steroids, vol. 58, pp. 185-189 (1993).
Tokes, et al, J. Org. Chem., vol. 32 (4), pp. 1020-1029 (1967).
Copy of Tetredron Letters, vol. 31, No. 24 pp. 3475-3476 1990.
Copy of Chem. Abstracts, vol. 85, 1976 pp. 662-663 No. 13, Sep. 27, 1976.
Copy of Chem. Abstracts. vol. 111, 1989 p. 796, No. 9.

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