Process for the preparation of 11.beta.,21-dihydroxy-2'-methyl-5

Details Process for the preparation of 11.beta.,21-dihydroxy-2'-methyl-5 Process for the preparation of 11.beta.,21-dihydroxy-2'-methyl-5

1981-12-23

1984-02-14

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing a...

C12P 3302

Patent

active

044317328

ABSTRACT:
A process for preparing 11.beta.,21-dihydroxy-2'-methyl-5'.beta.H-1,4-pregnadieno(16,17-d)-oxazole -3,20-dione, comprises fermenting 11.beta.,21-dihydroxy-2'-methyl-5'.beta.H-4-pregneno (16,17-d)-oxazole-3,20-dione with a living culture of Arthrobacter simplex.

REFERENCES:
patent: 2981659 (1961-04-01), Fonken et al.
patent: 3274182 (1966-09-01), Dryden et al.
patent: 3560486 (1971-02-01), Marx et al.
patent: 3684656 (1972-08-01), van der Waard
patent: 3718673 (1973-02-01), Ripka
patent: 4101378 (1978-07-01), Nishikawa et al.
patent: 4246346 (1981-01-01), Larsson et al.
Charney, Microbial Transformations of Steroids, Academic Press, New York, 1967, p. 356 ff.

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