Process for the preparation of...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C546S194000, C546S203000

Reexamination Certificate

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09525894

ABSTRACT:
A process for preparing 10,11-dihydro-5H-dibenzo[a,d]cyclohept-5-enes (e.g. loratadine) by reacting a dibenzozuberone with an aliphatic ketone in the presence of low valent titanium.

REFERENCES:
patent: 6084100 (2000-07-01), Stampa et al.
patent: 6093827 (2000-07-01), Jackson
Honrubia et al., Chem. Pharm. Bull., 45(5), 842-848, 1997.
Cid et al., Tetrahedron, 44(19), 6197-6200, 1988.

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