Process for the preparation of 1-(thiomethyl)-cyclopropaneacetic

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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549 15, 558347, C07C 6104

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055234771

ABSTRACT:
The present invention provides a novel process for the preparation of 1,1-cyclopropanedimethanol cyclic sulfite which comprises: (a) contacting 1,1-cyclopropanedimethanol with dialkylsulfite in the presence of a base; and (b) removing from the reaction mixture the alcohol reaction by-product. This process is incorporated in the additional novel processes for preparing 1-(hydroxymethyl)cyclopropaneacetonitrile and 1-(thiomethyl)cyclopropaneacetic acid.

REFERENCES:
patent: 4596879 (1986-06-01), Fizet
patent: 5270324 (1993-12-01), Zamboni et al.
patent: 5350760 (1994-09-01), LaBelle
patent: 5438141 (1995-08-01), LaBelle
U.S. Ser. No. 08/350,428 Dec. 9, 1994, to McNamara et al. (Case 19156IA).

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