Process for the preparation of 1-(aminomethyl)...

Details Process for the preparation of 1-(aminomethyl)... Process for the preparation of 1-(aminomethyl)...

2008-07-01

2008-07-01

Oh, Taylor Victor (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C514S561000

Reexamination Certificate

active

10433241

ABSTRACT:
A conversion process of gabapentin hydrochloride into gabapentin comprising: a) dissolution of gabapentin hydrochloride in a solvent in which the gabapentin hydrochloride and the gabapentin are completely soluble; and b) subsequent addition of an amine that allows the removal of the chloride ion from the solution containing gabapentin hydrochloride, by precipitation of the hydrochloride of the same amine, leaving the gabapentin in solution in free amino acid form.

REFERENCES:
patent: 4024175 (1977-05-01), Satzinger
patent: 4960931 (1990-10-01), Butler
patent: 5068413 (1991-11-01), Steiner
patent: 6255526 (2001-07-01), Pesachovich et al.
patent: WO 98/28255 (1998-07-01), None
Grant et al , chemical dictionary , 1987, p. 220.

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