Process for the preparation of 1-aminomethyl-1-cyclohexaneacetic

Details Process for the preparation of 1-aminomethyl-1-cyclohexaneacetic Process for the preparation of 1-aminomethyl-1-cyclohexaneacetic

1990-08-21

1992-02-25

Shippen, Michael L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

548408, 548554, 560126, 562504, 562553, 564448, C07C 6108

Patent

active

050915673

ABSTRACT:
The instant invention concerns a novel process for the preparation of 1-aminomethyl-1-cyclohexaneacetic acid (gabapentin), a known compound useful for treating certain cerebral diseases such as epilepsy and dizziness.

REFERENCES:
patent: 2812334 (1957-11-01), Moffett et al.
patent: 2825739 (1958-03-01), Allen
patent: 3253039 (1966-05-01), Rylander
patent: 3417090 (1968-12-01), Pelster
patent: 3594419 (1971-07-01), Rosenthal
patent: 3595875 (1971-07-01), Larkin
patent: 3624127 (1971-11-01), Shaw et al.
patent: 3624127 (1971-11-01), Shaw et al.
patent: 3766271 (1973-10-01), Knifton
patent: 4024175 (1977-05-01), Satzinger et al.
patent: 4087544 (1978-05-01), Satzinger et al.
patent: 4894476 (1990-01-01), Butler et al.
Journal of the American Chemical Society, v. 83, No. 7, Apr. 19, 1961, pp. 1733-1738, W. S. Wadsworth et al., "The Utility of Phosphanate Carbanions in Olefin Synthesis".
Organic Preparations and Procedures International, v. 19, No. 6, 1987, pp. 471-475, Richard A. Bunce et al, "Michael Reaction of Nitromethane with Beta, Beta-Disubstituted Acrylate Esters".
Copending U.S. Application 399056, Filed 8-25-89.

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