Process for the preparation of 1-alkyl-pyrazole-5-carboxylic aci

Details Process for the preparation of 1-alkyl-pyrazole-5-carboxylic aci Process for the preparation of 1-alkyl-pyrazole-5-carboxylic aci

1998-01-08

1999-11-02

Stockton, Laura L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D23114

Patent

active

059773782

ABSTRACT:
1-alkyl-pyrazole-5-carboxylic acid esters are prepared by reacting the enolate of a 2,4-diketocarboxylic acid ester with an N-alkylhydrazinium salt in the presence of a solvent. This process allows a particularly economic preparation of 1-alkyl-pyrazole-5-carboxylic acid esters in a simple manner and with only little formation of undesirable isomers.

REFERENCES:
patent: 5462960 (1995-10-01), Barth et al.
Patent Abstracts of Japan (JP 61 040266 A) vol. 10, No. 199 (C-359) [2255], Jul. 11, 1986.
Patent Abstracts of Japan (JP 59 196868 A) vol. 9, No. 59 (C-270) [1782], Mar. 15, 1985.
Patent Abstracts of Japan (JP 07 118238 A) vol. 0 95, No. 008, Sep. 29, 1995.
W. Theilheimer "Synthetic Methods of Organic Chemistry" 1962, S. Karger XP002058626, vol. 16, 428; p. 204.
W. Theilheimer "Synthetic Methods of Organic Chemistry" 1984, S. Karger XP002058627, vol. 38, 412; p. 166.
W. Theilheimer "Synthetic Methods of Organic Chemistry" 1975, S. Karger XP002058628, vol. 2, 368; p. 128.
W. Theilheimer "Synthetic Methods of Organic Chemistry" 1952, S. Karger XP002058629, vol. 6, 403; p. 148.
A.R. Katritsky et al.: "Comprehensive Heterocyclic Chemistry", 1984, Pergamon Press XP002058630, vol. 5, pp. 277-282.
Chem. Ber. 59, (1926), p. 1282.
Chem. Ber. 59, (1996), p. 603.
J. Prakt. Chem. 26, (1930), p. 198.
Austr. J. Chem. 36, (1983), pp. 135-147.
Seki et al., Chem. Pharm. Bull., 32(4), pp. 1568-1577, 1984.

Affiliated with

Also associated with

Rating

Process for the preparation of 1-alkyl-pyrazole-5-carboxylic aci does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of 1-alkyl-pyrazole-5-carboxylic aci, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of 1-alkyl-pyrazole-5-carboxylic aci will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2137395