Process for the preparation of 1-alkyl-3-carboxy-4-cinnolones

Details Process for the preparation of 1-alkyl-3-carboxy-4-cinnolones Process for the preparation of 1-alkyl-3-carboxy-4-cinnolones

1988-03-23

1990-09-11

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544235, 549439, 560 34, 562439, 562868, C07D23728, C07D491056

Patent

active

049564609

ABSTRACT:
A process for the preparation of 1-alkyl-3-carboxy-4-cinnolones of formula I ##STR1## wherein R and R.sub.1 are electron donor groups and R.sub.3 is an alkyl group, starting from an amine of formula II ##STR2## which is subjected to the following transformations; (1) diazotation;

REFERENCES:
patent: 2797218 (1957-06-01), Barber et al.
patent: 3485845 (1969-12-01), Davis et al.
patent: 3669965 (1972-06-01), White
patent: 3937704 (1976-02-01), Stranotmann et al.
patent: 4495351 (1985-01-01), Schmidt et al.
"Advanced Organic Chemistry" by Jerry March (3rd. Ed.) p. 485 (1985).
Comprehensive Heterocyclic Chemistry, vol. 3, Part 2B, pp. 42-43, "The Structure, Reactions, Synthesis and Uses of Heterocylic Compounds", Pergamon Press (1984).

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