Process for the preparation of 1,4-dihydropyridinedicarboxylic e

Details Process for the preparation of 1,4-dihydropyridinedicarboxylic e Process for the preparation of 1,4-dihydropyridinedicarboxylic e

1997-02-14

1998-09-15

Morris, Patrica L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21102

Patent

active

058080848

ABSTRACT:
Benzylidene intermediates, useful in the preparation of dihydropyridines such as nifedipine and amlodipine, are formed by reaction of a ketocarboxylic adid ester with an aldehyde in the presence of a catalytic amount of dimethylamine acetate.

REFERENCES:
patent: 4600778 (1986-07-01), Teller et al.

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