Process for the preparation of 1,4-diazabicyclo-(2,2,2)-octane

Details Process for the preparation of 1,4-diazabicyclo-(2,2,2)-octane Process for the preparation of 1,4-diazabicyclo-(2,2,2)-octane

1979-10-15

1981-09-15

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C07D29502

Patent

active

042898811

ABSTRACT:
A process for the preparation of 1,4-diazobicyclo-(2,2,2)-octane by contacting piperazine with a catalyst at an elevated temperature, the catalyst containing silicon dioxide.

REFERENCES:
patent: 2985658 (1961-05-01), Krause
patent: 3166558 (1965-01-01), Masaoli
patent: 3956329 (1976-05-01), Murakami et al.
Ohhashi et al., Chem. Abs. 84, 180284m.

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