Process for the preparation of 1-(4-chlorobenzoyl)-5-methoxy-2-m

Details Process for the preparation of 1-(4-chlorobenzoyl)-5-methoxy-2-m Process for the preparation of 1-(4-chlorobenzoyl)-5-methoxy-2-m

1983-02-25

1986-04-29

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D20928

Patent

active

045858802

ABSTRACT:
The invention relates to a process for the preparation of the known 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetoxyacetic acid which comprises reacting an indolecarboxylic acid of Formula (II) or its derivative with an alcohol of Formula (III). The final product is known to have antiinflammatory activity.

REFERENCES:
patent: 2518456 (1950-08-01), Fein et al.
patent: 4332727 (1982-06-01), Boltze et al.
Fisherova et al., Chem. Abst. 90:87267x (1979).

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