Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1995-06-07
1998-01-20
Daus, Donald G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
C07D47504
Patent
active
057102716
ABSTRACT:
A process for the preparation, separation and purification of (6S) and (6R) diastereomers of folinic acid salts with at least dibasic amines is disclosed, which process comprises the hydrolysis of (6RS)-5,10-methenyl-5,6,7,8-tetrahydrofolic acid chloride hydrochloride with an at least dibasic amine and the subsequent separation of the diasteromeric salts.
REFERENCES:
patent: 2737515 (1956-03-01), Brockman
patent: 4148999 (1979-04-01), Temple et al.
patent: 4206307 (1980-06-01), Temple et al.
patent: 4500711 (1985-02-01), Wisowaty et al.
patent: 5010194 (1991-04-01), Mueller
patent: 5239074 (1993-08-01), Marazza et al.
patent: 5300505 (1994-04-01), Mueller et al.
patent: 5382581 (1995-01-01), Marazza
patent: 5446156 (1995-08-01), Jequier
patent: 5489684 (1996-02-01), Jequier
patent: 5599931 (1997-02-01), Ripa et al.
Distaso Carlo
Felder Ernst
Ripa Giorgio
Daus Donald G.
Dibra S.p.A.
LandOfFree
Process for the preparation and separation of diastereomeric sal does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for the preparation and separation of diastereomeric sal, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation and separation of diastereomeric sal will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-726357