Process for the preparatin of .beta.-lactam compounds

Details Process for the preparatin of .beta.-lactam compounds Process for the preparatin of .beta.-lactam compounds

1991-08-30

1998-05-12

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Sulfur-oxidation, epimerization, 6-alkoxylation,...

540205, 540221, 540301, C07D49904

Patent

active

057506841

ABSTRACT:
The present invention provides a process for the substitution of an acylamino .beta.-lactam compound at the carbon atom carrying the acylamino group, which process comprises reacting the .beta.-lactam compound with an halogenating agent and a nucleophilic reagent; characterized in that the acylamino group has an acidic group on the carbon atom adjacent the carbonyl group.
In particular the process of this invention comprises reacting a .beta.-lactam of partial structure (I): ##STR1## where X represents an acidic group; with an halogenating agent and a nucleophilic reagent.

REFERENCES:
patent: 4447602 (1984-05-01), Firestone et al.
The Journal of Organic Chemistry, vol. 38, No. 7, pp. 1436-1437, Apr. 6, 1973.
Journal of the American Chemical Society, vol. 95, No. 7, pp. 2403-2404, Apr. 4, 1973.
Lann et al., Tetrahedron Letters, No. 14, pp. 1311-1313, (1974).
The Journal of Organic Chemistry, vol. 38. No. 7, Apr. 6, 1973, pp. 1436-1437.
Journal of the American Chemical Society, vol. 95, No.7, Apr. 4, 1973, pp. 2403-2404.
W.H.W. Lunn et al.Tetrahedron Letters, No. 14, pp. 1311-1313, (1974).

Affiliated with

Also associated with

Rating

Process for the preparatin of .beta.-lactam compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparatin of .beta.-lactam compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparatin of .beta.-lactam compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-980194