Process for the optical determination of lipase

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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424 2, 435 19, G01N 3315, G01N 100, G01N 3348, C12Q 144

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049884972

ABSTRACT:
The present invention provides a lipase substrate of the general formula: ##STR1## wherein A is an alkalene or alkenylene radical containing up to 16 carbon atoms, R and R.sub.1, which can be the same or different, each signify an alkyl, alkenyl or acyl radical containing up to 20 carbon atoms or an optionally alkyl-substituted aryl or aralkyl radical containing up to 8 carbon atoms in the alkyl moiety and wherein one of R and R.sub.1 can also be a hydrogen atom, X is the residue of an aromatic hydroxy or thiol compound, and each Y and Z, independently from each other, is --S-- or --O--, Z also --CH.sub.2 --.
The present invention also provides a process and a reagent for the optical determination of lipase.

REFERENCES:
patent: 3689364 (1972-09-01), Hartel et al.
patent: 3986930 (1976-10-01), Kurooka et al.
patent: 4343897 (1982-08-01), Neumann et al.
patent: 4667032 (1987-05-01), Lau et al.

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