Process for the mineralization of collagen fibers, product produ

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 12, 530356, A61K 3712, C07K 1400, C08H 106, C08L 8900

Patent

active

055322174

ABSTRACT:
There is disclosed a process for the mineralization of collagen fibers whereby collagen fibers formed from collagen are contacted with a solution of calcium and phosphate ions under conditions to effect nucleation and in-vitro growth of mineral crystals within and on the surface of the collagen fibers to form intact collagen fibers with subfibrillar substructure and wherein preparations of such mineralized collagen fibers are used in bone replacement therapy as well as to induce repair in bony defects.

REFERENCES:
patent: 3443261 (1969-05-01), Battisla et al.
patent: 4776890 (1988-10-01), Chu
patent: 5231169 (1993-07-01), Constanz et al.

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