Process for the microbiological preparation of human serum album

Details Process for the microbiological preparation of human serum album Process for the microbiological preparation of human serum album

1989-12-13

1991-08-06

Weimar, Elizabeth C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 698, 4351723, 4351721, 4353201, 530350, 530362, 530364, 935 41, 935 29, 935 44, 935 45, C12P 2102, C12N 1570, C12N 1514, C07K 1300

Patent

active

050377442

ABSTRACT:
Human serum albumin is made by culturing a bacterium (e.g. E. coli) capable of providing for the stable maintenance of a plasmid containing an inducible promoter (e.g. P.sub.trp), a ribosome binding site (e.g. that of the CII gene of bacteriophage lambda not containing the t.sub.R1 sequence), and the human serum albumin gene possessing an ATG initiation codon at the 5' end.

REFERENCES:
patent: 4511502 (1985-04-01), Builder et al.
patent: 4551433 (1985-11-01), DeBoer
patent: 4578355 (1986-03-01), Rosenberg
patent: 4792523 (1988-12-01), Wong et al.
patent: 4831120 (1989-05-01), Aviv et al.
patent: 4914027 (1990-03-01), Knapp et al.
Beaucage et al. (1981) Deoxy Nucleoside Phosphoramidites--A New Class of Key Intermediates for Deoxypolynucleotide Synthesis, Tetrahedron Letters, 22, 1859-1862.
Proceedings of the National Academy of Sciences of the USA, vol. 81, No. 3, Feb. 1984, pp. 669-673.

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