Process for the microbiological preparation of human serum album

Details Process for the microbiological preparation of human serum album Process for the microbiological preparation of human serum album

1986-03-25

1990-04-03

Warren, Charles F.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 698, 4351723, 4352523, 43525233, 435320, 530350, C12N 100, C12N 1500, C12P 2100, C12P 2102

Patent

active

049140272

ABSTRACT:
Human serum albumin is produced by culturing a bacterium (e.g. E. coli) capable of maintaining a plasmid containing an inducible promoter (e.g. P.sub.trp) upstream of the penicillin amidase promoter, the ribosome binding site of the penicillin amidase gene and the penicillin amidase signal peptide, fused with the structural gene for human serum albumin.

REFERENCES:
patent: 4382028 (1983-05-01), Paget
patent: 4551433 (1985-11-01), Deboer
patent: 4666836 (1987-05-01), Inouye et al.
Nishi et al, Agric. Biol. Chem., vol. 48, pp. 669-675 (1984).
Lawn et al, Nucleic Acids Research, vol. 9, pp. 6103-6114 (1981).

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