Process for the manufacture of spiro-linked pyrrolidine 2,5-dion

Details Process for the manufacture of spiro-linked pyrrolidine 2,5-dion Process for the manufacture of spiro-linked pyrrolidine 2,5-dion

1987-07-10

1988-06-07

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544 70, 544230, 546 15, C07D27910, C07D29508, C07D24100

Patent

active

047497890

ABSTRACT:
This invention relates to novel processes for the manufacture of spiro-linked pyrrolidine-2,5-diones of the formula; ##STR1## which have a potent inhibitory activity on aldose reductase and are useful for reduction and prevention of chronic diabetic complications.
The invented processes are useful as improved and convenient method for a large scale manufacture.

REFERENCES:
patent: 4443465 (1984-04-01), Brittain et al.
patent: 4593092 (1986-06-01), Irikura et al.
Takagi et al., Chem. Abstracts. vol. 104, 5884s (1986).

Affiliated with

Also associated with

Rating

Process for the manufacture of spiro-linked pyrrolidine 2,5-dion does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the manufacture of spiro-linked pyrrolidine 2,5-dion, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the manufacture of spiro-linked pyrrolidine 2,5-dion will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-845644