Process for the manufacture of prolonged action vincamine prepar

Details Process for the manufacture of prolonged action vincamine prepar Process for the manufacture of prolonged action vincamine prepar

1981-07-27

1983-01-18

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

525347, A61K 31795

Patent

active

043691757

ABSTRACT:
The invention relates to a process for the manufacture of prolonged action and stable vincamine preparations, which process comprises reacting an acid addition salt of vincamine with an alkali metal salt or alkaline earth metal salt of a sulfonic acid cation exchange resin, in particular an alkali metal salt of a sulfonated copolymer of styrene with a small amount of divinyl benzene, in a polar reaction medium such as water. The invention further relates to the vincamine preparations so obtained, to the use thereof for the manufacture of ready-for-use medicaments for oral administration and to these medicaments themselves.

REFERENCES:
patent: 2990332 (1961-06-01), Keating
patent: 3313686 (1967-04-01), Bryan et al.

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