Process for the manufacture of pharmaceutical grade ranitidine b

Details Process for the manufacture of pharmaceutical grade ranitidine b Process for the manufacture of pharmaceutical grade ranitidine b

1994-06-24

1997-12-09

Trinh, Ba K.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D30752

Patent

active

056962754

ABSTRACT:
A process for the manufacture of pharmaceutical grade ranitidine l-2-nitro-1, 1-ethenediamine), is described. In-vitro and in-vivo pharmacological studies and acute toxicity studies indicate that it is as active and as safe as Form 2 ranitidine hydrochloride.

REFERENCES:
patent: 4128658 (1978-12-01), Price et al.
patent: 4521431 (1985-06-01), Crookes
patent: 4968808 (1990-11-01), Mosdorf et al.

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