Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1978-07-17
1979-03-13
Torrence, Dolph H.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
C07C12004, C07C12166
Patent
active
041442652
ABSTRACT:
Quaternary ammonium salts, such as methyl tributyl ammonium chloride, are novel catalysts in a nitrile-forming reaction which comprises stirring together aqueous sodium cyanide and the undistilled m-trifluoromethyl benzyl chloride product of the reaction of chloromethyl methyl ether, chlorosulfonic acid and trifluoromethyl benzene from which chloromethyl ether impurities, methanol, water and some of the unreacted trifluoromethyl benzene are removed. The process is conducted under alkaline conditions in a two-phase liquid reaction medium. m-Trifluoromethyl benzyl nitrile is prepared in excellent yields and purity.
REFERENCES:
patent: 3573032 (1971-03-01), Fellig et al.
patent: 3992432 (1976-11-01), Napier et al.
patent: 4056509 (1977-11-01), Verbrugge et al.
Hennis et al., I&EC Product Research and Development, vol. 7, pp. 96-101 (1968).
Yadav, Chemical Industry Developments, p. 21 (1975).
Dehmlow, Chem. Tech., p. 216 (1975).
Reeves et al., Synthetic Communications, vol 6., No. 3, pp. 193-197 (1976).
Weber et al., Phase Transfer Catalysis in Organic Synthesis, pp. 98-101 (1977).
Dowd William
Fisher Thomas H.
Dankert Lester J.
Hill Joyce P.
The Dow Chemical Company
Torrence Dolph H.
LandOfFree
Process for the manufacture of m-trifluoromethyl benzyl nitrile does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for the manufacture of m-trifluoromethyl benzyl nitrile, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the manufacture of m-trifluoromethyl benzyl nitrile will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2371446