Process for the manufacture of layered tablets incorporating con

Details Process for the manufacture of layered tablets incorporating con Process for the manufacture of layered tablets incorporating con

1977-02-11

1978-09-12

White, Robert F.

Plastic and nonmetallic article shaping or treating: processes

Forming articles by uniting randomly associated particles

Stratified or layered articles

264120, 264122, B29C 600

Patent

active

041138163

ABSTRACT:
The present invention relates to the manufacture of new tablets for administration of medicaments, which tablets contain in their mass, controlled-release microcapsules, that is to say elemental particles coated with a protective covering which contains an encapsulated product which is gradually released in a controlled, regular and time-dependent way.
These new tablets are characterized in that they are constituted by the association of a plurality of superposed layers of which the medial layer is essentially constituted by microcapsules containing an active substance, while the exterior layers constitute means of protecting the microcapsules of the medial layer, particularly against the shock of compression when compressing them to tablets. The invention thus relates to a process for manufacturing said tablets.

REFERENCES:
patent: 3096248 (1963-07-01), Rudzki
patent: 3723589 (1973-03-01), Kennedy

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