Process for the manufacture of intermediates in camptothecin...

Details Process for the manufacture of intermediates in camptothecin... Process for the manufacture of intermediates in camptothecin...

2006-02-17

2008-09-09

Seeman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07423152

ABSTRACT:
The present invention provides a process for the manufacture of the compound of formula (1):which is a key intermediate in the manufacture of camptothecin (CPT). This compound continues to serve as an attractive and promising lead structure for the development of new anti-cancer drugs.

REFERENCES:
patent: 6063923 (2000-05-01), Fang et al.
Wall et al., Am. Chem. Soc., 3, pp. 327 (1993).
Thomas et al., Bioorg. Med. Chem., 12, pp. 1585-1604 (2004).
Ciufolini et al., Targets in Hetercyclic Systems, 4, pp. 25-55 (2000).
Ciufolini et al., Tetrahedron, 53, pp. 11049-11060 (1997).
Comins et al., J. Am. Chem. Soc., 114, pp. 10971-10972 (1992).
Tan et al., Tetrahedron, 58, pp. 7403-7410 (2002).
Comins et al., J. Org. Chem., 59, pp. 5120-5121 (1994).
Comins et al., Tetrahedron Lett., 35, pp. 5331-5334 (1994).
Peters, et al., Org. Biomol. Chem., 4, pp. 498-509 (2006).

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