Process for the manufacture of human transferrin labelled with i

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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2523011R, A61K 4300

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active

039392589

ABSTRACT:
A process for the manufacture of human transferrin labelled with indium 113 m is provided, wherein an acid eluate of an indium 113 m generator having an activity concentration of 0.1 to 50 m Curie per ml is added dropwise to an aqueous solution containing 3 to 10 mg of sodium bicarbonate per 5 to 100 mg of human transferrin per ml. The solution may also contain hydrochloric acid or sodium chloride and a bacteriostatic agent.

REFERENCES:
"Red Cell and Plasma Protein Labeling with .sup.113m In," International Journal of Applied Radiation and Isotopes, 1971, Vol. 22, No. 8, pp. 498-501.
Chemical Abstracts, Vol. 75, No. 19, Nov. 8, 1971, p. 78, Item No. 116531b.
Chemical Abstracts, Vol. 72, No. 15, Apr. 13, 1970, p. 85, Item No. 75562e.

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