Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1979-12-10
1981-10-06
Berch, Mark L.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
546208, 546209, 544 60, 546210, 546212, 544 62, 546213, 546214, 544111, 546256, 546270, 544131, 546271, 546275, 544133, 546276, 546277, 544134, 546278, 546280, 544135, 546281, 546283, 544137, 546284, 544 16, 544138, 544 30, 546207, 544139, 544140, 544146, 544149, 544152, 544337, 544359, 544364, 544366, 544367, 544368, 544369, 544370, 544374, 544379, 2602454, 2603303, 2603474, 546193, 546194, 546198, 546199, 546205, C07D20508, C07D40314, C07D40304, C07D40312
Patent
active
042934621
ABSTRACT:
The invention concerns a process for the manufacture of 7.beta.-amino-3-cephem-3-ol-4-carboxylic acid compounds by ring closure of esters of 2-[4-(substituted-thio)-3-acylamino-2-oxoazetidin-1-yl]-3-substituted-amin o-crotonic acids and solvolyzing the enamino group in the resulting 7.beta.-acylamino-3-substituted-amino-cephem-4-carboxylic acid esters.
REFERENCES:
patent: 3950352 (1976-04-01), Wolfe
patent: 3959266 (1976-05-01), Pall'Asta
patent: 3960881 (1976-06-01), Kulkolja et al.
patent: 3975383 (1976-08-01), Naylor et al.
patent: 4036835 (1977-07-01), Foglio et al.
patent: 4079181 (1978-03-01), Tsuji et al.
Woodward et al., Chem. Abs. 8e, 29052, (1976).
Bickel Hans
Woodward Robert B.
Almaula Prabodh I.
Berch Mark L.
Ciba-Geigy Corporation
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