Process for the manufacture of diazinon

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

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C07F 965

Patent

active

043236782

ABSTRACT:
The invention provides an improved process for the manufacture of the insecticide diazinon. The process uses .beta.-isobutyrylaminocrotonic acid amide as starting material and, by reaction with sodium hydroxide solution or alcoholate and phosphorylation with diethylthiophosphoryl chloride, diazinon (0,0-diethyl-0-(2-isopropyl-4-methyl-6-pyrimidinyl)thiono -phosphate) is obtained directly in a high yield without isolating any intermediates.

REFERENCES:
patent: 2754243 (1956-07-01), Gysin et al.
patent: 2928864 (1960-03-01), Tabor
patent: 3798220 (1974-03-01), Klemm et al.
patent: 3862273 (1975-01-01), Kroposki et al.
patent: 4012506 (1977-03-01), Balke et al.
patent: 4052397 (1977-10-01), Blackwell et al.

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