Process for the manufacture of bioerodible poly (orthoester)s an

Details Process for the manufacture of bioerodible poly (orthoester)s an Process for the manufacture of bioerodible poly (orthoester)s an

1991-07-24

1993-05-18

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424484, A61F 200

Patent

active

052119513

ABSTRACT:
A process for the manufacture of bioerodible poly(ortho ester)s and polyacetals containing beneficial agents having a hydroxyl functionality of two or more and their fabrication into controlled release dosage forms having a reproducible delivery of the beneficial agent into the biological environment of use are disclosed.

REFERENCES:
patent: 4814183 (1989-03-01), Zentner
patent: 5047464 (1991-09-01), Pogany et al.
D. R. Day, et al., Micromet Instruments Publication No. CA0001, "Cure Monitoring: A Comparison of Dielectric and Thermal Analysis", Micromet Instruments, Inc., 26 Landsdowne Street, Suite 150, Cambridge, MA, 02139.
LaVerne Leonard, Micromet Instruments Publication No. RP0019, "Microdielectrometry: Tiny Sensors Close the Cure Control Loop", Reprinted from Advanced Composites, Jan./Feb. 1987.
M. L. Bromberg, et al., Micromet Instruments Publication No. RP0009, "New Applicatins for Dielectric Monitoring and Control", Micromet Instruments, Inc., 26 Landsdowne Street, Suite 150, Cambridge, MA, 02139, pp. 307-311.
M. Connoly and B. Tobias, American Laboratory, Jan. (1992), 38-42.
R. W. Biernath, et al., "Dynamic Microdielectric Monitoring of Epoxy/Phenolic Cure", Department of Chemical Engineering, University of California at Berkeley, Berkeley, CA, 94720.

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