Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lipoproteins – e.g. – egg yolk proteins – cylomicrons – etc.
Patent
1991-03-11
1992-02-18
Doll, John
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lipoproteins, e.g., egg yolk proteins, cylomicrons, etc.
C07K 302, C07K 312, A61K 356, A61K 3700
Patent
active
050896024
ABSTRACT:
Apolipoproteins are isolated from human blood plasma fractions which contain apolipoproteins by suspending these fractions in buffer solutions. The suspensions are subsequently incubated with a lower aliphatic alcohol, either with or without an organic solvent. The phase which contains the lipoproteins is separated and concentrated. The products obtained according to the procedure may be used primarily for the treatment of cardiovascular diseases, in particular hypercholesterolemia.
REFERENCES:
Mezdour et al. J. of Chromatography, 414 (1987) 35-45.
Heiniger Hans J.
Isliker Henri
Lerch Peter G.
Morgenthaler Jean J.
Peitsch Manuel C.
Doll John
Koh Choon P.
Rotkreuzstiftung Zentrallaboratorium Blutspendedienst SRK
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