Process for the manufacture of amino compounds fixed to carriers

Details Process for the manufacture of amino compounds fixed to carriers Process for the manufacture of amino compounds fixed to carriers

1973-11-23

1976-05-11

Spear, Jr., Frank A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

195 68, 210 22R, 2601125R, B01D 1300

Patent

active

039561135

ABSTRACT:
Process of fixing peptide-type compounds to a carrier by reacting a cyanide compound and a reagent containing positive halogen with a polyhydroxy compound in an alkaline medium, removing low molecular components from the resultant reaction mixture, reacting the cross-linked activated product thus obtained with a water-soluble amino compound capable of substitution on at least one basic nitrogen atom, and subjecting the reaction mixture to dialysis or filtration.

REFERENCES:
patent: 3281331 (1966-10-01), Bergkvist
patent: 3403146 (1968-09-01), Hunt
patent: 3645852 (1972-02-01), Axen et al.
patent: 3674767 (1972-07-01), Lilly et al.

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