Process for the manufacture of a pharmaceutical composition with

Details Process for the manufacture of a pharmaceutical composition with Process for the manufacture of a pharmaceutical composition with

1983-09-20

1984-11-20

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424 19, 424 38, A61K 926, A61K 942

Patent

active

044838476

ABSTRACT:
The present invention provides a process for the production of a pharmaceutical composition with a retarded liberation of active material, wherein an active material in finely divided form is mixed with a finely divided high melting and a low melting lipid or lipoid component, the mixture is brought to a temperature which is above the melting point of the low melting component but below the melting point of the high melting component and the mixture, after melting of the low melting component, is allowed to cool to below the melting point thereof and subsequently worked up in known manner to give a finished pharmaceutical composition.

REFERENCES:
patent: 2875130 (1959-02-01), Grass et al.
patent: 3108046 (1963-10-01), Harbit et al.
patent: 3146167 (1964-08-01), Lantz et al.
patent: 3184386 (1965-05-01), Stephenson
patent: 3279998 (1966-10-01), Raff et al.
patent: 3308217 (1967-03-01), Lowy et al.
patent: 3374146 (1968-03-01), Blicharz et al.
patent: 3670065 (1972-06-01), Erickson et al.
patent: 4132753 (1979-01-01), Bilchare et al.

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